Endocrine active substances
Any substance that interacts or interferes with normal hormonal activity is an endocrine active substance.
The Endocrine Active Substances Information System (EASIS) is a web accessible database that provides information on endocrine active properties of chemical substances.
EASIS contains information on endocrine activity of chemicals as well as adverse effects that may be linked to an endocrine activity. This can help you get a picture of a substance’s potential to be an endocrine disruptor, that is when it alters the function of the endocrine system and consequently causes adverse effects (according to the endocrine disruptor definition of IPCS/WHO, 2002).
EASIS currently contains data on over 600 chemicals collected from around 10,000 study entries covering in vitro and in vivo assays in different species, including some human data.
Data on chemicals come from scientific studies that have been further independently peer-reviewed and presented in a standardised format, using the OECD Harmonised Templates (OHTs). This ensures compatibility with other international data collection undertakings.
Data also follow the ‘FAIR' data management principles: Findability, Accessibility, Interoperability, and Reuse.
Access EASIS database
What’s behind EASIS?
EASIS is based on IUCLID 6 and uses a common OECD format to present data.
Need help to use EASIS?
EASIS is easy to use! But still, some hints and pointers might be useful.